Things to do on a San Pedro de Atacama to Punta Arenas Road Trip

The journey begins in San Pedro de Atacama, but don’t rush off too quickly - this region is one of the most unique landscapes on Earth. The Atacama Desert is the driest non-polar desert in the world, and its scenery feels closer to Mars than planet Earth.

Start with the iconic:

• Valle de la Luna - Known for its jagged salt formations, dunes, and fiery sunsets

• Valle de la Muerte - Perfect for sandboarding or catching golden hour over endless ridgelines

These spots are just minutes from town but feel completely otherworldly.

Other must see's before heading off are:

• Miscanti and Miñiques Lagoons – Deep blue lakes framed by volcanoes at over 4,000m altitude

• El Tatio Geysers – One of the largest geyser fields in the world

• Salar de Atacama – Chile’s largest salt flat

• Laguna Chaxa – A prime spot to see flamingos against a surreal white landscape

As you leave San Pedro de Atacama and head toward Antofagasta:

• Expect long, empty roads with dramatic mountain backdrops

• Pass abandoned mining towns

• The sense of isolation is part of the experience - fuel up and plan stops carefully

Breaking up your journey in Santiago is a great way to recharge before heading further south. Surrounded by the Andes, the city offers a striking contrast to the remote desert landscapes you’ve just experienced.

• Take in panoramic views from Cerro San Cristóbal

• Wander through vibrant neighbourhoods like Bellavista and Lastarria for cafés, street art, and nightlife

• Visit local markets such as La Vega Central for an authentic taste of Chile

• Stock up on supplies and enjoy a proper meal before continuing your road trip

It’s the perfect midway reset offering culture, comfort, and a chance to experience Chile’s urban energy before diving back into nature.

One of Chile’s most scenic regions:

• Puerto Varas - Overlooks Llanquihue Lake with volcano views

• Osorno Volcano - Picture-perfect cone-shaped volcano

• Lush forests, waterfalls, and alpine-style villages

For adventurous travellers:

• Carretera Austral - One of the world’s most beautiful drives

• Remote landscapes, glaciers, rivers, and minimal crowds

A true highlight of the trip:

• Torres del Paine National Park - Granite peaks, turquoise lakes, and wildlife

• Hiking, photography, and jaw-dropping scenery at every turn

As you approach the southern tip:

• Windswept landscapes and unique wildlife

• Possible penguin sightings

End your journey in Punta Arenas:

• Gateway to Antarctica

• Visit historic sites and coastal viewpoints

• Reflect on one of the most diverse road trips on Earth

Relocations through Imoova are ideal for long-distance routes like this:

• Huge distances = massive savings potential

• Flexible travel with accommodation included

• A rare chance to experience the full length of Chile on a backpacker budget

You can find Imoova's South American relocations here.